Risk factors and predictive model of adrenocortical insuffi ciency in patients with traumatic brain injury

作     者：Gui-long Feng Miao-miao Zheng Shi-hong Yao Yin-qi Li Shao-jun Zhang Wei-jing Wen Kai Fan Jia-li Zhang Xiao Zhang Gui-long Feng;Miao-miao Zheng;Shi-hong Yao;Yin-qi Li;Shao-jun Zhang;Wei-jing Wen;Kai Fan;Jia-li Zhang;Xiao Zhang

作者机构：Department of Emergencythe First Hospital of Shanxi Medical UniversityTaiyuan 030001China Department of EmergencyZhenjiang First People’s HospitalZhenjiang 212000China Department of EmergencyYuncheng Central HospitalYuncheng 044500China Department of Endocrinologythe Fourth Affi liated HospitalZhejiang University School of MedicineYiwu 322000China 

出 版 物：《World Journal of Emergency Medicine》 (世界急诊医学杂志（英文）)

年 卷 期：2021年第12卷第3期

页      面：179-184页

核心收录：

学科分类：1002[医学-临床医学] 100210[医学-外科学(含：普外、骨外、泌尿外、胸心外、神外、整形、烧伤、野战外)] 100201[医学-内科学(含：心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 10[医学] 

基　　金：a grant from the National Clinical Specialty Construction Project of China(2013-544) 

主　　题：Adrenocortical insuffi ciency Risk factor Predictor Traumatic brain injury 

摘      要：BACKGROUND:Neuroendocrine dysfunction after traumatic brain injury(TBI)has received increased attention due to its impact on the recovery of neural *** purpose of this study is to investigate the incidence and risk factors of adrenocortical insuffi ciency(AI)after TBI to reveal independent predictors and build a prediction model of AI after ***:Enrolled patients were grouped into the AI and non-AI *** preset impact factors were *** were regrouped according to each impact factor as a categorical *** and multiple logistic regression analyses were performed to screen the related independent risk factors of AI after TBI and develop the predictive ***:A total of 108 patients were recruited,of whom 34(31.5%)patients had *** factors(age,Glasgow Coma Scale[GCS]score on admission,mean arterial pressure[MAP],urinary volume,serum sodium level,cerebral hernia,frontal lobe contusion,diff use axonal injury[DAI],and skull base fracture)were probably related to AI after *** factors(urinary volume[X4],serum sodium level[X5],and DAI[X8])were independent variables,based on which a prediction model was developed(logit P=-3.552+2.583X4+2.235X5+2.269X8).CONCLUSIONS:The incidence of AI after TBI is *** such as age,GCS score,MAP,urinary volume,serum sodium level,cerebral hernia,frontal lobe contusion,DAI,and skull base fracture are probably related to AI after *** volume,serum sodium level,and DAI are the independent predictors of AI after TBI.