Atrial fibrillation in patients with systolic heart failure:pathophysiology mechanisms and management

作     者：Ioanna Koniari Eleni Artopoulou Dimitrios Velissaris Nicholas Kounis Grigorios Tsigkas Ioanna Koniari;Eleni Artopoulou;Dimitrios Velissaris;Nicholas Kounis;Grigorios Tsigkas

作者机构：Manchester Heart InstituteManchester University Foundation TrustManchesterUnited Kingdom Department of Internal MedicineUniversity Hospital of PatrasPatrasGreece Department of CardiologyUniversity Hospital of PatrasPatrasGreece 

出 版 物：《Journal of Geriatric Cardiology》 (老年心脏病学杂志（英文版）)

年 卷 期：2021年第18卷第5期

页      面：376-397页

核心收录：

学科分类：1002[医学-临床医学] 100201[医学-内科学(含：心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 10[医学] 

主　　题：prevention diagnosis management 

摘      要：Heart failure(HF)and atrial fibrillation(AF)demonstrate a constantly increasing prevalence during the 21st century worldwide,as a result of the aging population and the successful interventions of the clinical practice in the deterioration of adverse cardiovascular *** and AF share common risk factors and pathophysiological mechanisms,creating the base of a constant *** impairs systolic and diastolic function,resulting in the increasing incidence of HF,whereas the structural and neurohormonal changes in HF with preserved or reduced ejection fraction increase the possibility of the AF *** temporal relationship of the development of either condition affects the diagnostic algorithms,the prognosis and the ideal therapeutic strategy that leads to euvolaemia,management of noncardiovascular comorbidities,control of heart rate or restoration of sinus rate,ventricular synchronization,prevention of sudden death,stroke,embolism,or major bleeding and maintenance of a sustainable quality of *** indicated treatment for the concomitant HF and AF includes rate or/and rhythm control as well as thromboembolism prophylaxis,while the progress in the understanding of their pathophysiological interdependence and the introduction of the genetic profiling,create new paths in the diagnosis,the prognosis and the prevention of these diseases.