Antibiotic Bone Cement and Ultraviolet Light Use in Total Knee Arthroplasty
Antibiotic Bone Cement and Ultraviolet Light Use in Total Knee Arthroplasty作者机构：The Center for Hip and Knee Surgery St. Francis Hospital Mooresville Mooresville Indiana USA
出 版 物：《Open Journal of Orthopedics》 (矫形学期刊（英文）)
年 卷 期：2016年第6卷第9期
页 面：283-293页
学科分类：1002[医学-临床医学] 100210[医学-外科学(含：普外、骨外、泌尿外、胸心外、神外、整形、烧伤、野战外)] 10[医学]
主 题：Antibiotic Bone Cement Ultraviolet Light Total Knee Arthroplasty Infection Complications
摘 要：Objective: The purpose of this study was to determine usefulness of antibiotic bone cement and UV light in primary Total Knee Arthroplasty (TKA). Patients and Methods: Between 1986 and 2008, 3105 TKAs were performed using 750 mg of cefuroxime per bag of cement (Group 1), 7537 using cefuroxime and UV light (Group 2), and 4573 using UV light and gentamicin premixed (Group 3). Results: The primary infection rate was 0.57% (87 acute postoperative infections). Of these, 27 (0.9%) were in Group 1, 44 (0.6%) were in Group 2, and 16 (0.35%) were in Group 3 (p = 0.0013). Kaplan-Meier survival in Groups 1 - 3 for reoperation for aseptic loosening of any component at 5 years was 0.9908, 0.9927, and 0.9959, respectively (p = 0.1315). Conclusion: Despite potential concerns mentioned in the literature, these results continue to support the use of antibiotic bone cement and UV lights during TKA.
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