Serum Level of Vitamin C in a Sample of Egyptian Patients with Multiple Sclerosis

作     者：Asmaa Ibrahim Taha K. Alloush Yousry Abo Elnaga Mohamed Hamdy Mohamed M. Fouad 

作者机构：Department of Neurology Faculty of Medicine Ain Shams University Cairo Egypt 

出 版 物：《Neuroscience & Medicine》 (神经系统科学与医药（英文）)

年 卷 期：2019年第10卷第4期

页      面：398-406页

学科分类：1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学] 

主　　题：Vitamin C Multiple Sclerosis 

摘      要：Background: Antioxidants such as vitamin C can eliminate free radicles responsible for oxidative stress. Objective: To assess the serum level of vitamin C in a sample of multiple sclerosis (MS) patients to investigate a possible role of vitamin C in the pathogenesis of MS. Subjects and Methods: Forty patients with MS and twenty healthy controls were included in this study. Vitamin C level was estimated for each participant. Results: Serum vitamin C levels were significantly lower among the patients (ranging from 0.28 mg/dL to 0.75 mg/dL with mean 0.47 ± 0.14 mg/dL and median of 0.46 mg/dL) compared to controls (ranging from 0.60 mg/dL to 2.90 mg/dL with mean 1.87 ± 0.61 mg/dL and median of 1.90 mg/dL) (P Conclusion: Patients with MS tended to have low serum vitamin C levels, and younger patients had lower serum levels.