Significant reduction of humoral response to SARS-CoV-2 4 months after the diagnosis of COVID-19

作     者：Kang Zhang Zhen-Guo Ma Lei Yang Wei Kang Yun Yin Johnson Yiu-Nam Lau 

作者机构：University Hospital and Faculty of MedicineMacao University of Science and TechnologyMacao SARChina Department of Cardiology Renmin Hospital of Wuhan UniversityWuhan 430060China Hubei Key Laboratory of Metabolic and Chronic DiseasesWuhan 430060China The First affiliated HospitalSun Yat-Sen UniversityGuangzhou 510080China School of BusinessMacao University of Science and TechnologyMacao SARChina Department of Applied Biology and Chemical TechnologyHong Kong Polytechnic UniversityHong Kong SARChina 

出 版 物：《Precision Clinical Medicine》 (精准临床医学（英文）)

年 卷 期：2021年第4卷第1期

页      面：73-76页

学科分类：1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学] 

主　　题：humoral response antibodies COVID-19 SARS-CoV-2 

摘      要：Editor’s note A commentary on“Humoral immune response to SARS-CoV-2 in Iceland.Humoral response to COVID-19 disease,including IgM and IgG antibodies against SARS-CoV-2 virus,is well documented.1,2 Neutralizing activities against SARS-CoV-2 virus have also been confirmed in patients who have recovered from COVID-19.2 These observations form the basis for the assumption that SARS-CoV-2 vaccines can be developed through stimulation of the host immune system to generate neutralizing antibodies to SARS-CoV-2 virus.