Inhibition of CXCR4/CXCL12 signaling:a translational perspective for Alzheimer’s disease treatment
Inhibition of CXCR4/CXCL12 signaling: a translational perspective for Alzheimer’s disease treatment作者机构:The Shmunis School of Biomedicine and Cancer ResearchGeorge S.Wise Faculty of Life SciencesTel Aviv UniversityTel AvivIsrael
出 版 物:《Neural Regeneration Research》 (中国神经再生研究(英文版))
年 卷 期:2022年第17卷第1期
页 面:108-109页
核心收录:
学科分类:0710[理学-生物学] 1002[医学-临床医学] 1001[医学-基础医学(可授医学、理学学位)] 100203[医学-老年医学] 10[医学]
摘 要:The mechanism of AD remains uncovered:The current mainstream doctrine in Alzheimer’s disease(AD)is the amyloid cascade *** to this hypothesis,amyloid-β(Aβ)deposition is the main reason for neurofibrillary tangles formation and synaptic dysfunction.