pSVPoMCAT微基因修饰雪旺氏细胞移植治疗实验性脊髓损伤的酶及免疫组化评价(英文)
Evaluation of enzyme histochemistry and immunohistochemistry on microgene pSVPoMcat implanted to modify schwann cells in treating experimental spinal cord injury作者机构：General Hospital of Chengdu Military Command Chengdu 610083 China Huaxi Hospital Sichuang University Chengdu 610041 China
出 版 物：《中国组织工程研究》 (Chinese Journal of Tissue Engineering Research)
年 卷 期：2002年第6卷第6期
页 面：906-907页
学科分类：0710[理学-生物学] 0831[工学-生物医学工程（可授工学、理学、医学学位）] 1002[医学-临床医学] 100210[医学-外科学(含：普外、骨外、泌尿外、胸心外、神外、整形、烧伤、野战外)] 10[医学]
主 题：spinal cord injury microgene enzyme histochemistry immunohistochemistry
摘 要：Objective To provide morphological evidence for therapeutic effects of microgene pSVPoMcat implanted to modify schwann cells(SC) on the experimental spinal cord injury(SCI).Methods Experimental animals were divided into three groups: the group of microgene pSVPoMcat implanted to genetically SC(group A),SC implanted group(group B) and the control group(group C),each groups having 10 ***(AchE) and acid phosphatase(ACP)activity of anterior horn cells in the A,B,C groups were measured respectively with the quantitative enzyme histochemistry ;The number of axon in the spinal white matter was surveyed in the three groups by means of the quantitative immunohitochemistry. Results (1)AchE activity of anterior horn cells in the A,B,C groups were AB C;(2)The number of axon in a certain area of spinal white matter in the A,B,C were A B *** The therapeutic effects of microgene pSVPoMcat implanted to modify SC on the experimental SCI have the reliable morphological evidence.
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