Pharmacological perspectives and molecular mechanisms of coumarin derivatives against virus disease
作者机构：Department of Pharmacology&Key Laboratory of Gastrointestinal Pharmacology of Chinese Materia Medical of the State Administration of Traditional Chinese MedicineSchool of PharmacyThe Fourth Military Medical UniversityXi'anShanxi 710032PR China School of NursingArmy Medical University(Third Military Medical University)Chongqing 400038PR China Precision Pharmacy&Drug Development CenterThe Fourth Military Medical UniversityXi'anShanxi 710032PR China
出 版 物：《Genes & Diseases》 (基因与疾病（英文）)
年 卷 期：2022年第9卷第1期
页 面：80-94页
核心收录：
学科分类：1007[医学-药学(可授医学、理学学位)] 100705[医学-微生物与生化药学] 1001[医学-基础医学(可授医学、理学学位)] 100103[医学-病原生物学] 10[医学]
主 题：Coumarin Hepatitis virus Human immunodeficiency virus Infection Molecular mechanism
摘 要：Infections caused by viruses are one of the foremost causes of morbidity and mortality in the *** a number of antiviral drugs are currently used for treatment of various kinds of viral infection diseases,there is still no available therapeutic agent for most of the viruses in clinical *** is a chemical compound which is found naturally in a variety of plants,it can also be synthetically produced possessing diverse biological *** recently,reports have highlighted the potential role of coumarin derivatives as antiviral *** review outlines the advances in coumarin-based compounds against various viruses including human immunodeficiency virus,hepatitis virus,herpes simplex virus,Chikungunya virus and Enterovirus 71,as well as the structure activity relationship and the possible mechanism of action of the most potent coumarin derivatives.
维普期刊数据库