Feasibility and safety of “bridging” pancreaticogastrostomy for pancreatic trauma in Landrace pigs
作者机构：Department of Hepatopancreatobiliary SurgeryPeking University Shougang HospitalBeijing 100144China Faculty of Hepato-Pancreato-Biliary SurgeryInstitute of Hepatobiliary Surgery of Chinese PLAKey Laboratory of Digital Hepetobiliary SurgeryChinese PLA General HospitalBeijing 100853China
出 版 物：《World Journal of Gastrointestinal Surgery》 (世界胃肠外科杂志（英文版）（电子版）)
年 卷 期：2021年第13卷第5期
页 面：419-428页
核心收录：
学科分类：1002[医学-临床医学] 100210[医学-外科学(含：普外、骨外、泌尿外、胸心外、神外、整形、烧伤、野战外)] 10[医学]
主 题：Pancreatic trauma Damage control surgery “Bridging”pancreaticogastrostomy Severe pancreatic injury Safety
摘 要：BACKGROUND In recent years,we created and employed a new anastomosis method,“bridgingpancreaticogastrostomy,to treat patients with extremely severe pancreatic *** surgery has advantages such as short length of surgery,low secondary trauma,rapid construction of shunts for pancreatic fluid,preventing second surgeries,and achieving good treatment outcomes in clinical ***,due to the limited number of clinical cases,there is a lack of strong evidence to support the feasibility and safety of this surgical ***,we carried out animal experiments to examine this procedure,which is reported *** To examine the feasibility and safety of a new rapid method of pancreaticogastrostomy,“bridging*** Ten Landrace pigs were randomized into the experimental and control groups,with five pigs in each group.“Bridgingpancreaticogastrostomy was performed in the experimental group,while routine mucosa-to-mucosa pancreaticogastrostomy was performed in the control *** surgery,the general condition,amylase levels in drainage fluid on Days 1,3,5,and 7,fasting and 2-h postprandial blood glucose 6 mo after surgery,fasting,2-h postprandial peripheral blood insulin,and portal vein blood insulin 6 mo after surgery were *** was carried out at 1 and 6 mo after the former one to examine the condition of the abdominal cavity and firmness and tightness of the pancreaticogastric anastomosis and *** After surgery,the general condition of the animals was *** in the control group did not gain weight 6 mo after surgery,whereas significant weight gain was present in the *** were significant differences on Days 1 and 3 after surgery between the two groups but no differences on Days 5 and *** were no differences in fasting and 2-h postprandial blood glucose and fasting and 2-h insulin values of postprandial peripheral blood and portal vein blood 6 mo after surgery between the two ***
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