Recent advances in N-heterocyclic carbene-catalyzed radical reactions

作     者：Lei Dai Song Ye Lei Dai;Song Ye

作者机构：Beijing National Laboratory for Molecular SciencesCAS Key Laboratory of Molecular Recognition and Function.CAS Research/Education Center for Excellence in Molecular SciencesInstitute of ChemistryChinese Academy of SciencesBeijing 100190China University of Chinese Academy of SciencesBejing 100049China 

出 版 物：《Chinese Chemical Letters》 (中国化学快报（英文版）)

年 卷 期：2021年第32卷第2期

页      面：660-667页

核心收录：

学科分类：07[理学] 070303[理学-有机化学] 0703[理学-化学] 

基　　金：the financial support from the National Natural Science Foundation of China (Nos.21672216,21831008) the Beijing National Laboratory for Molecular Sciences (No. BNLMS-CXXM-202003)。 

主　　题：N-Heterocyclic carbene Radical Photocatalysis Organocatalysis SET 

摘      要：The N-heterocyclic carbene(NHC)-catalyzed reactions involving two-electron reaction pathway have been well-established.However,the development of NHC-catalyzed radical reactions is still in its infancy in terms of reaction types and enantioselectivity.In the past decade,several elegant NHC-catalyzed radical reactions have been developed,including NHC-catalyzed oxidation of aldehydes to esters,reductive coupling reactions using Breslow intermediate as SET reductant and NHC-catalyzed reactions via radical homoenolates,dienoaltes and trienolates.This review summarizes the recent advances in NHC-catalyzed reactions involving radical intermediates.