Time-domain terahertz optoacoustics: manipulable water sensing and dampening

作     者：Jiao Li Yixin Yao Liwen Jiang Shuai Li Zhihao Yi Xieyu Chen Zhen Tian Weili Zhang 

作者机构：Tianjin UniversitySchool of Precision Instruments and Optoelectronics EngineeringTianjinChina Tianjin UniversityCenter for Terahertz WavesTianjinChina Ministry of EducationKey Laboratory of Optoelectronics Information and TechnologyTianjinChina Oklahoma State UniversitySchool of Electrical and Computer EngineeringStillwaterOklahomaUnited States 

出 版 物：《Advanced Photonics》 (先进光子学（英文）)

年 卷 期：2021年第3卷第2期

页      面：89-97页

核心收录：

学科分类：0809[工学-电子科学与技术（可授工学、理学学位）] 08[工学] 

基　　金：This work was supported by the National Key Research and Development Program of China(2017YFA0701004) the National Natural Science Foundation of China(61675145,61722509,81771880,61735012,and 61420106006) the Tianjin Municipal Government(19JCQNJC12800).J.L.,Y.X.Y.,and L.W.J.contributed equally to this work.The authors declare no conflicts of interest 

主　　题：terahertz optoacoustics terahertz pulse time-domain detection label-free water 

摘      要：Radiation at terahertz frequencies can be used to analyze the structural dynamics of water and biomolecules,but applying the technique to aqueous solutions and tissues remains challenging since terahertz radiation is strongly absorbed by *** this absorption enables certain analyses,such as the structure of water and its interactions with biological solutes,it limits the thickness of samples that can be analyzed,and it drowns out weaker signals from biomolecules of *** present a method for analyzing water-rich samples via time-domain terahertz optoacoustics over a 104-fold thickness ranging from microns to *** demonstrate that adjusting the temperature to alter the terahertz optoacoustic(THz-OA)signal of water improves the sensitivity with which it can be analyzed and,conversely,can reduce or even“silenceits ***-manipulated THz-OA signals of aqueous solutions allow detection of solutes such as ions with an order of magnitude greater sensitivity than terahertz time-domain spectroscopy,and potentially provide more characteristic parameters related to both terahertz absorption and ultrasonic *** optoacoustics may be a powerful tool for spectroscopy and potential imaging of aqueous solutions and tissues to explore molecular interactions and biochemical processes.