Gene expression profiles of peripheral blood mononuclear cells from patients with atopic dermatitis stimulated with Malassezia globosa

作     者：Mao Lu Ya-Ling Dai Xin Ran Sushmita Pradhan Hai-Rong Liu Mei Ou Hong-Mei Wu Yu-Ping Ran Mao Lu;Ya-Ling Dai;Xin Ran;Sushmita Pradhan;Hai-Rong Liu;Mei Ou;Hong-Mei Wu;Yu-Ping Ran

作者机构：Department of DermatovenereologySichuan University West China HospitalChengduSichuan 610041China Department of DermatovenereologyThe First Affiliated Hospital of Chengdu Medical CollegeChengduSichuan 610500China Department of Laboratory MedicineThe First Affiliated Hospital of Chengdu Medical CollegeChengduSichuan 610500China. 

出 版 物：《Chinese Medical Journal》 (中华医学杂志（英文版）)

年 卷 期：2021年第134卷第22期

页      面：2759-2761页

核心收录：

学科分类：1002[医学-临床医学] 100206[医学-皮肤病与性病学] 10[医学] 

基　　金：the Research Project of Sichuan Provincial Education Department(No.17ZA0127) the 1.3.5 Project for Disciplines of Excellence,West China Hospital,Sichuan University,and the HX-Academician Project,West China Hospital,Sichuan University 

主　　题：patients dermatitis pathogenesis 

摘      要：To the Editor:Malassezia located in the skin of patients with atopic dermatitis(AD)might be related to its pathogenesis,consisting of Malassezia globosa and Malassezia restricta as the dominant species.[1]However,the specific molecular mechanisms of Malassezia on host immune cells from AD patients are still *** our study,the Affymetrix Human Prime View array was used to detect the effect of *** on the gene expression of peripheral blood mononuclear cells(PBMCs)from AD patients,which was favorable to further understand the role of Malassezia colonization in the pathogenesis of AD.