Effects of Semi-Ablative Fractional Radiofrequency Associated with Growth Factors in Stretch Marks: A Randomized Controlled Trial

作     者：Patricia F. Meyer Rodrigo Marcel V. Da Silva Liliane S. Vasconcelos Louhanne Christine B. Bezerra Maria Paula M. Oliveira Eneida M. Carreiro Ciro D. Soares Fabio S. Borges Monica Etrusco Joyce Rodrigues Silene B. Ribeiro Hernan Andrés B. Ortiz Patricia F. Meyer;Rodrigo Marcel V. Da Silva;Liliane S. Vasconcelos;Louhanne Christine B. Bezerra;Maria Paula M. Oliveira;Eneida M. Carreiro;Ciro D. Soares;Fabio S. Borges;Monica Etrusco;Joyce Rodrigues;Silene B. Ribeiro;Hernan Andrés B. Ortiz

作者机构：Federal University of Rio Grande do Norte (UFRN) Natal Brazil Physiotherapy Course at UNIRN Natal Brazil Mauricio de Nassau Natal Natal Brazil Physiotherapy Course at Potiguar University (UnP) Natal Brazil Potiguar University (UnP) Natal Brazil Graduate Program in Stomatopathology State University of Campinas Sã o Paulo Brazil Postgraduate Program in Dermatofunctional Physiotherapy Estácio de Sá University Rio de Janeiro Brazil Minas Gerais Faculty of Medical Sciences Minas Gerais Brazil Sã o Judas Tadeu University Butantã  Brazil FSG Centro Universitário Caxias do Sul Brazil Physiotherapy Course Escuela de Kinesiología Facultad de Ciencias de la Rehabilitación Universidad Andrés Bello Santiago Chile 

出 版 物：《Open Journal of Applied Sciences》 (应用科学（英文）)

年 卷 期：2021年第10卷第4期

页      面：379-394页

学科分类：07[理学] 0701[理学-数学] 070101[理学-基础数学] 

主　　题：Striae Distensae Collagen Wound Healing 

摘      要：Background: To investigate the effects of the association of semi-ablative fractional radiofrequency (RFF) with growth factors in stretch marks. Methods: This is a randomized controlled trial. The sample consisted of 28 female patients with complaints of gluteus or abdomen striae and divided into 2 equitable groups, named G1 (semi-ablative RFF without active principle association) and G2 (semi-ablative RFF with active principle association), being subdivided into G-1A and G-2A (abdominal applications) and G-1B and G-2B (gluteus applications). A photographic and histological analysis was performed using questionnaires about inflammation, presence of adverse effects and satisfaction of volunteers. Photographic analysis showed a reduction in the amount of striae alba in all groups. Results: The histological analysis showed an increase in fibroblast activity, collagen type I, and blood vessels, especially in the groups that associated the RFF with the active principle. In the inflammation analysis, the groups that performed intervention with active ingredients showed lower inflammatory signal. All groups had a reasonable level of satisfaction after the interventions;however, the group that used active ingredients reported greater results. Conclusion: The association of semi ablative RFF with growth factors showed a reduction in clinical inflammatory signs, mainly in the first 15 days, as well as higher collagen production, verified in 30 days, with satisfactory clinical results in all groups.