The advantage of low-dose clomiphene citrate for overweight women with anovulation

作     者：Ping-Ping Sun Na Sun Yue-Min Zhang Jin-Guang Wang Hua-Gang Ma 

作者机构：The Reproductive Medicine Centre of Weifang People's HospitalWeifang 261041ShandongChina. 

出 版 物：《Drug Combination Therapy》 (药物联合治疗)

年 卷 期：2021年第3卷第2期

页      面：29-34页

学科分类：1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学] 

主　　题：Clomiphene citrate Ovulation promotion Overweight Obesity Multiple follicle Endometrium thickness 

摘      要：Background:To investigate the potential advantage of using low-dose clomiphene citrate to promote ovulation in women with overweight or ***:The patients with overweight were divided randomly into regular clomiphene citrate group(clomiphene citrate 50 mg/d,n=83)and low-dose clomiphene citrate group(clomiphene citrate 25 mg/d,n=105).All patients received treatment from the 5th day of their menstrual ***:Luteinizing hormone levels and estradiol levels were more increased in the low-dose group compared with the regular group(P0.05).Conclusion:The low-dose clomiphene citrate treatment significantly reduced the number of mature follicles and increased the thickness of endometrium on the human chorionic gonadotropin day with less side *** low-dose clomiphene citrate also achieved the better ovulation rate.