Synthesis and characterization of macrocyclic compounds with a hydroxyl functional group

作     者：Min Ou Chun Zhu Qi-Long Zhang Bi-Xue Zhu 

作者机构：Key Laboratory of Macrocyclic and Supramolecular ChemistryGuizhou University Department of ChemistryGuiyang Medical College 

出 版 物：《Chinese Chemical Letters》 (中国化学快报（英文版）)

年 卷 期：2013年第24卷第10期

页      面：869-872页

核心收录：

学科分类：07[理学] 070303[理学-有机化学] 0703[理学-化学] 

基　　金：supported by the National Natural Science Foundation of China(No.21061003) he International Collaborative Project of Guizhou Province(No.700104) the Natural Science Foundation of the Guizhou Province(No.(2012)2151) 

主　　题：Schiff base Macrocyclic compound Synthesis Structure 

摘      要：A novel [1＋1] Schiff-base macrocyclic compound 3 has been synthesized from precursor 1, 1,3-bis（2＇- formylphenoxy）-2-propanol, and precursor 2, resorcinol-bis（4-aminophenyl）ether, via condensation and cyclizaction using Ba2＋ as template. The macrocycle 3 was further reduced giving saturated macrocycle 4. The structures of 3 and 4 were characterized by elemental analysis, ~H NMR, IR, and MS spectra, and their structures were determined via single crystal X-ray diffraction studies. X-ray diffraction analysis revealed that the macrocyclic compound 3 has a folded conformation, and the corresponding reduced product 4 adopts a twisted and folded conformation due to its flexible nature. ~ 2013 Bi-Xue Zhu. Published by Elsevier B.V. on behalf of Chinese Chemical Society. All rights reserved.