The Relationship between Abnormal Circadian Blood Pressure Rhythm and Risk of Readmission in Patients with Heart Failure with Preserved Ejection Fraction
作者机构：Department of Cardiologythe First People’s Hospital of Fuyang District in HangzhouHangzhou311400China Department of Cardiologythe Second Affi liated Hospital of Chongqing Medical UniversityChongqing400010China
出 版 物：《Cardiovascular Innovations and Applications》 (心血管创新与应用（英文）)
年 卷 期：2021年第5卷第2期
页 面：275-282页
学科分类：083002[工学-环境工程] 0830[工学-环境科学与工程（可授工学、理学、农学学位）] 08[工学]
主 题：Heart failure with preserved ejection fraction circadian blood pressure rhythm ambulatory blood pressure monitoring riser pattern N-terminal pro-B-type natriuretic peptide readmission
摘 要：Objective:Abnormal circadian blood pressure rhythm has been revealed to be associated with hypertensive target organ damage and cardiovascular events,but its association with readmission risk in patients with heart failure with preserved ejection fraction(HFpEF)remains *** conducted a retrospective study to explore the relationship between circadian blood pressure rhythm and readmission risk in HFpEF ***:We retrospectively collected baseline and follow-up data on HFpEF patients who underwent ambulatory blood pressure monitoring(ABPM)from May 2015 to October *** circadian blood pressure rhythms defi ned by ABPM were grouped as dipper,nondipper,or riser *** and multivariate linear regression analyses were performed to assess the association between circadian blood pressure rhythm and readmission ***:A total of 122 patients were enrolled in this *** mean age and ejection fraction were 69.87 years and 61.44%,respectively,with mean the N-terminal pro-B-type natriuretic peptide(NT-proBNP)level being 1048.15 pg/*** were signifi cant differences in the 24-hour systolic blood pressure(SBP),sleep SBP,and sleep diastolic blood pressure(DBP)among the three groups,where the 24-hour SBP,sleep SBP,and sleep DBP in the riser pattern group were markedly higher than in the dipper pattern ***,serum NT-proBNP levels,the proportion of patients readmitted for heart failure and the mean number of admissions differed markedly among three ***,multivariate linear regression analysis showed that the riser pattern was a signifi cant and independent risk factor for increased serum NT-proBNP level(β=929.16,95%confi dence interval 178.79–1679.53,P=0.016).In multivariate logistic regression analysis,the riser pattern was demonstrated to be a signifi cant risk factor for readmission(odds ratio 11.23,95%confi dence interval 2.01–62.67,P=0.006)in HFpEF ***:The riser blood pressure pattern is a
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