Cerebral venous sinus thrombosis in polycythemia vera patients with JAK2V617F mutation

作     者：Hui-Xin Shen Xiao-Qin Huang Chun-Qiu Fan Yan-Xiang Cao Hong Zhao Jian-Gang Duan Shen Hui-Xin;Huang Xiao-Qin;Fan Chun-Qiu;Cao Yan-Xiang;Zhao Hong;Duan Jian-Gang

作者机构：Department of NeurologyXuanwu HospitalCapital Medical UniversityBeijing 100053China Department of RadiologyXuanwu HospitalCapital Medical UniversityBeijing 100053China Department of HematologyXuanwu HospitalCapital Medical UniversityBeijing 100053China Department of EmergencyXuanwu HospitalCapital Medical UniversityBeijing 100053China 

出 版 物：《Chinese Medical Journal》 (中华医学杂志（英文版）)

年 卷 期：2021年第134卷第10期

页      面：1251-1253页

核心收录：

学科分类：1002[医学-临床医学] 100204[医学-神经病学] 10[医学] 

基　　金：supported by grants from the Capital Medical University in 2017(No.17JL-02,2017-2019) the National Key Research and Development Program of China(Nos.2016YFC1300600,2017-2020,2016YFC0901004,2017-2020) 

主　　题：venous Cerebral thrombosis 

摘      要：To the Editor:Polycythemia vera(PV)[1]is a chronic progressive myeloproliferative neoplasm(MPN)characterized by clonal proliferation of myeloid *** condition presents with a high number of abnormal erythrocytosis,leukocytosis,and thrombocytosis,which may lead to venous *** venous sinus thrombosis(CVST)is a rare presentation of PV in clinical *** of PV are often insidious during the onset,and a lack of specific clinical manifestations of CVST may lead to delayed *** date,diagnosis and management of CVST in PV remain a challenge due to the low incidence and limited *** this study,we presented five cases of PV with JAK2V617F mutation,and CVST was the first manifestation of *** detailed characteristics are summarized in Table *** Institute Ethics Committee of Xuanwu Hospital,Capital Medical University approved this study(approval number 2019119).The authors certify that they have obtained all appropriate patient consent forms.