Enantioseparation of 3-chlorophenylglycine enantiomers using Mandyphos-Pd as chiral extractant

作     者：Xiong Liu Shuhuan Chen Yu Ma Wenjie Xiao Xiong Liu;Shuhuan Chen;Yu Ma;Wenjie Xiao

作者机构：School of Chemistry and Chemical EngineeringHunan University of Science and TechnologyXiangtan 411201China Hunan Provincial Key Laboratory of Controllable Preparation and Functional Application of Fine PolymersXiangtan 411201China 

出 版 物：《Chinese Journal of Chemical Engineering》 (中国化学工程学报（英文版）)

年 卷 期：2021年第34卷第5期

页      面：96-103页

核心收录：

学科分类：081704[工学-应用化学] 07[理学] 070304[理学-物理化学(含∶化学物理)] 08[工学] 0817[工学-化学工程与技术] 0703[理学-化学] 

基　　金：This work was financially supported by National Natural Science Foundation of China(Grant No.51703060) Hunan Provincial Innovation Foundation for Postgraduate(Grant No.CX2018B673) 

主　　题：Enantioseparation Mandyphos 3-Chlorophenylglycine Response surface method Recognition mechanism 

摘      要：Chiral extractant plays a key role in chiral extraction,and considerable efforts have been undertaken for the development of new and efficient chiral extractants in recent *** work demonstrated for the first time that chiral ferrocenyl diphosphine ligand(Mandyphos-Pd)had considerable ability to enantioseparate 3-Chlorophenylglycine enantiomers with separation factor(α)of ***-Pd concentration and pH had significant influences on enantioselectivity,while operating temperature showed less *** extraction experiments can be performed at room temperature(20℃)which had the advantage of energy *** optimization,the highest performance factor(pf,0.08376)was obtained at the condition of pH 7.8 and Mandyphos-Pd concentration 1.2 mmol·L^(-1).According to the experimental results,the possible recognition mechanism was discussed.