Association of changes in waist circumference with cardiovascular disease and all-cause mortality among the elderly Chinese population: a retrospective cohort study

作     者：Xue-Ning ZHANG Hao ZHAO Zhan SHI Ling YIN Xiao-Yan ZHAO Chun-Yu YIN Yong-Li YANG Song-He SHI Xue-Ning ZHANG;Hao ZHAO;Zhan SHI;Ling YIN;Xiao-Yan ZHAO;Chun-Yu YIN;Yong-Li YANG;Song-He SHI

作者机构：Department of Epidemiology and BiostatisticsCollege of Public HealthZhengzhou UniversityZhengzhouHenanChina Department of PharmacyZhengzhou First People's HospitalZhengzhouHenanChina Department of NeurologyChinese People's Liberation Army General HospitalBeijingChina 

出 版 物：《Journal of Geriatric Cardiology》 (老年心脏病学杂志（英文版）)

年 卷 期：2021年第18卷第3期

页      面：185-195页

核心收录：

学科分类：1002[医学-临床医学] 100201[医学-内科学(含：心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 10[医学] 

基　　金：supported by the National Key Research and Development Programme of China(2017YFC1307705&2016YFC0106907) the Science and Technology Development Programme of Henan(No.201403007) 

主　　题：mortality among elderly 

摘      要：BACKGROUND To examine the association of baseline waist circumference(WC)and changes in WC with cardiovascular disease(CVD)and all-cause mortality among elderly *** A total of 30,041 eligible participants were included from a retrospective cohort in *** same questionnaire,anthropometric and laboratory measurements were performed at baseline(2010)and the first follow-up(2013).The percent change in WC between baseline and the first follow-up was calculated to evaluate three years change of *** collected the occurrence of CVD and all-cause death from the first follow-up to December 31,*** cubic splines and Cox proportionalhazards regression models were used to evaluate the relationship between baseline WC/changes in WC and *** The dose-response relationships between baseline WC and CVD mortality were U-or *** low WC group,compared with stable group,the fully adjusted hazard ratio(aHR)for CVD mortality was 1.60(95%CI:1.24−2.06)in WC gain group among *** normal WC group,the CVD mortality risk increased with WC gain(men:aHR=1.86,95%CI:1.36−2.56;women:aHR=1.83,95%CI:1.29−2.58).In moderate-high WC group,the CVD mortality risk increased with WC gain(men:aHR=1.76,95%CI:1.08−2.88;women:aHR=1.46,95%CI:1.04−2.05)and risk decreased with WC loss(men:aHR=0.54,95%CI:0.30−0.98;women:aHR=0.59,95%CI:0.37−0.96).CONCLUSIONS For the elderly population,WC gain may increase CVD mortality risk regardless of baseline WC,whereas WC reduction could decrease the risk only in the moderate-high WC group.