Marine-derived fungi as a source of bioactive indole alkaloids with diversifed structures
作者机构:College of Pharmaceutical SciencesInstitute of Life Science and Green DevelopmentHebei UniversityBaoding 071002China
出 版 物:《Marine Life Science & Technology》 (海洋生命科学与技术(英文))
年 卷 期:2021年第3卷第1期
页 面:44-61页
核心收录:
学科分类:0710[理学-生物学] 1007[医学-药学(可授医学、理学学位)] 100705[医学-微生物与生化药学] 07[理学] 071005[理学-微生物学] 10[医学]
基 金:This work was supported by the National Natural Science Foundation of China(Nos.41606174,21877025) the Scientific Research Foundation of Hebei educational committee(No.BJ2020048) the China Postdoctoral Science Foundation(No.2019M661045) the Natural Science Interdisciplinary Research Program of Hebei University(No.DXK201913)
主 题:Indole alkaloid Marine-derived fungus Chemical diversity Bioactivity
摘 要:Marine-derived fungi are well known as rich sources of bioactive natural *** evidences indicated that indole alkaloids,isolated from a variety of marine-derived fungi,have attracted considerable attention for their diverse,challenging structural complexity and promising bioactivities,and therefore,indole alkaloids have potential to be pharmaceutical lead *** compilation of the relevant *** this review,we demonstrated a comprehensive overview of 431 new indole alkaloids from 21 genera of marine-derived fungi with an emphasis on their structures and bioactivities,covering literatures published during 1982–2019.