Cervical Ripening for Induction of Labor: A Randomized Comparison between Vaginal Misoprostol versus Foley’s Catheter Placement in a Nigeria Tertiary Hospital

作     者：Matthew Igwe Nwali Joseph Agboeze Vitus Okwuchukwu Obi Arinze C. Ikeotuonye Ikechukwu Ogwudu Ugadu Emmanuel Ajuluchukwu Ugwa Matthew Igwe Nwali;Joseph Agboeze;Vitus Okwuchukwu Obi;Arinze C. Ikeotuonye;Ikechukwu Ogwudu Ugadu;Emmanuel Ajuluchukwu Ugwa

作者机构：Department of Obstetrics and Gynecology Federal Teaching Hospital Abakaliki Nigeria Department of Obstetrics and Gynecology Federal Medical Center Birnin Kudu Nigeria 

出 版 物：《Open Journal of Obstetrics and Gynecology》 (妇产科期刊（英文）)

年 卷 期：2021年第11卷第3期

页      面：252-262页

学科分类：12[管理学] 1204[管理学-公共管理] 120402[管理学-社会医学与卫生事业管理(可授管理学、医学学位)] 1004[医学-公共卫生与预防医学(可授医学、理学学位)] 10[医学] 

主　　题：Cervical Ripening Labor Induction Misoprostol Balloon Catheter 

摘      要：Background: Cervical ripening is prerequisite of successful induction of labor. Vaginal misoprostol and Foley’s catheter placement have been widely used for this purpose but the data are not always sufficient. We attempted to determine which (misoprostol versus Foley’s catheter) is more effective/safer in Nigerian setting. Methods: A randomized controlled trial was performed at Federal Teaching Hospital Abakaliki, Nigeria, involving 135 term pregnant women requiring cervical ripening and labor induction. Participants were randomly allocated to misoprostol versus catheter group. The following were recorded/measured/analyzed: Bishop’s score, age, parity, body mass index, gestational age, labor duration, indication, oxytocin use, mode of delivery, and Apgar score. Chi square test and t test were used where appropriate. Results: At 24 hours, all of misoprostol group were either in labor, had ripe cervix, or had delivered, whereas 35.4% of catheter group had still unripe cervix (x2 = 29.856, P = 0.0001). Misoprostol group was less likely to require oxytocin infusion (x2 = 52.600,span style=