A cynomolgus monkey with naturally occurring Parkinson's disease
A cynomolgus monkey with naturally occurring Parkinson’s disease作者机构：Key Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Sciences & Yunnan Province Kunming Institute of Zoology Chinese Academy of Sciences State Key Laboratory of Genetic Resources and Evolution Kunming Institute of Zoology Chinese Academy of Sciences Shenzhen Key Laboratory for Molecular Biology of Neural Development Guangdong Provincial Key Laboratory of Brain Connectome and Behavior CAS Key Laboratory of Brain Connectome and Manipulation The Brain Cognition and Brain Disease Institute Shenzhen Institutes of Advanced Technology Chinese Academy of Sciences China Kunming College of Life Science University of Chinese Academy of Sciences Institute of Neuroscience CAS Key Laboratory of Primate Neurobiology State Key Laboratory of NeuroscienceChinese Academy of Sciences National Resource Center for Non-Human Primates Kunming Primate Research Center and National Research Facility for Phenotypic & Genetic Analysis of Model Animals (Primate Facility) Kunming Institute of Zoology Chinese Academy of Sciences Max Planck Institute of Psychiatry Department of Translational Research in Psychiatry Department of Rehabilitation Medicine the Second People’s Hospital of Yunnan Province Center for Excellence in Brain Science and Intelligence Technology Chinese Academy of Sciences KIZ–CUHK Joint Laboratory of Bioresources and Molecular Research in Common Diseases Kunming Institute of Zoology Chinese Academy of Sciences Center for Excellence in Animal Evolution and Genetics Chinese Academy of Sciences
出 版 物：《National Science Review》 (国家科学评论(英文版))
年 卷 期：2021年第8卷第3期
页 面：17-20页
核心收录：
学科分类：1002[医学-临床医学] 100204[医学-神经病学] 10[医学]
基 金：supported by the Key-Area Research and Development Program of Guangdong Province (2019B030335001) the National Key R&D Program of China (2018YFA0801403) the Strategic Priority Research Program of the Chinese Academy of Sciences (CAS)(XDB32060200and XDB32020200) the National Program for Key Basic Research Projects (2015CB755605) the National Natural Science Foundation of China (81941014, 81471312, 81771387,81460352, 81500983, 31700897, 31700910,31800901, 31960178, 91732302) the Applied Basic Research Programs of Science and Technology Commission Foundation of Yunnan Province (2017FB109, 2018FB052, 2018FB053,2019FA007, 202001AT070130) the China Postdoctoral Science Foundation (2018M631105) CAS ‘Light of West China’ Program
摘 要：Evidence for the existence of monkeys with spontaneous Parkinson’s disease (PD) has been lacking. Here,we screened macaque colonies at the Kunming Primate Research Center(Association for Assessment and Accreditation of Laboratory Animal Care(AAALAC) accredited), Kunming Institute of Zoology, Chinese Academy of Sciences, which has a large population of monkeys (2400), to identify naturally occurring PD monkeys.
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