Unintended changes in ocular biometric parameters during a 6-month follow-up period after FS-LASIK and SMILE

作     者：Junjie Wang Bernardo T.Lopes Hechen Li Riccardo Vinciguerra Si Cao Songan Wu Rong Zhu Qinmei Wang Xiaobo Zheng Fangjun Bao Ahmed Elsheikh 

作者机构：Eye HospitalWenzhou Medical UniversityWenzhou 325027ZhejiangChina The Institution of Ocular BiomechanicsWenzhou Medical UniversityWenzhou 325027ZhejiangChina School of EngineeringUniversity of LiverpoolLiverpool L693GHUK Humanitas San Pio X HospitalMilanItaly National Institute for Health Research(NIHR)Biomedical Research Centre for OphthalmologyMoorfields Eye Hospital NHS Foundation Trust and UCL Institute of OphthalmologyLondonUK Beijing Advanced Innovation Center for Biomedical EngineeringBeihang UniversityBeijingChina 

出 版 物：《Eye and Vision》 (眼视光学杂志（英文）)

年 卷 期：2021年第8卷第1期

页      面：75-82页

核心收录：

学科分类：1002[医学-临床医学] 100212[医学-眼科学] 10[医学] 

基　　金：supported by the National Natural Science Foundation of China(82001924) Zhejiang Provincial Natural Science Foundation of China under Grant(LY20H120001,LQ20A020008) Science and Technology Plan Project of Wenzhou Science and Technology Bureau(Y20190638) 

主　　题：Posterior corneal surface Internal anterior chamber depth The length from corneal endothelium to retina FS-LASIK SMILE 

摘      要：Background:Corneal refractive surgery has become reliable for correcting refractive errors,but it can induce unintended ocular changes that alter refractive *** study is to evaluate the unintended changes in ocular biometric parameters over a 6-month follow-up period after femtosecond laser-assisted laser in situ keratomileusis(FS-LASIK)and small incision lenticule extraction(SMILE).Methods:156 consecutive myopic patients scheduled for FS-LASIK and SMILE were included in this *** corneal thickness(CCT),mean curvature of the corneal posterior surface(K_(pm)),internal anterior chamber depth(IACD)and the length from corneal endothelium to retina(ER)were evaluated before and after surgery over a 6-month ***:Both the FS-LASIK and SMILE groups(closely matched at the pre-surgery stage)experienced flatter Kpm,shallower IACD and decreased ER 1 week post-surgery(P0.01),and these changes were larger in FS-LASIK than in SMILE *** the 1 week to 6 months follow up period,K_(pm),IACD and ER remained stable unlike CCT which increased significantly(P0.05),more in the FS-LASIK ***:During the follow up,the posterior corneal surface became flatter and shifted posteriorly,the anterior chamber depth and the length from the corneal endothelium to retina decreased significantly compared with the pre-surgery *** unintended changes in ocular biometric parameters were greater in patients undergoing FS-LASIK than *** changes present clear challenges for IOL power calculations and should be considered to avoid affecting the outcome of cataract surgery.