Microfluidics in cardiovascular disease research: state of the art and future outlook
作者机构：School of PharmacyQingdao UniversityQingdao266071China Center for Prenatal DiagnosisZibo Maternal and Child Health Care HospitalZibo255000China Department of Clinical PharmacyThe Affiliated Hospital of Jiangsu UniversityJiangsu UniversityZhenjiang212001China Institute of Thermal Science and TechnologyShandong UniversityJinan250061China Center for Basic Medical ResearchTEDA International Cardiovascular HospitalChinese Academy of Medical Sciences&School of MedicineNankai UniversityTianjin300457China
出 版 物：《Microsystems & Nanoengineering》 (微系统与纳米工程（英文）)
年 卷 期：2021年第7卷第2期
页 面：1-19页
核心收录：
学科分类：1002[医学-临床医学] 100201[医学-内科学(含：心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 10[医学]
基 金：This work was supported by the National Science Foundation of China(22008130 and 51806123) the China Postdoctoral Science Foundation(2020M682124) the Natural Science Foundation of Tianjin(18JCYBJC42000) the Research Fund of TEDA International Cardiovascular Hospital(2018-TD-001) the Qingdao Postdoctoral Researchers Applied Research Project Foundation(RZ2000001426) the Scientific Research Foundation for Youth Scholars from Qingdao University(DC1900014265)
主 题：fluid versatile discussions
摘 要：Due to extremely severe morbidity and mortality worldwide,it is worth achieving a more in-depth and comprehensive understanding of cardiovascular *** effort has been made to replicate the cardiovascular system and investigate the pathogenesis,diagnosis and treatment of cardiovascular *** can be used as a versatile primary strategy to achieve a holistic picture of cardiovascular ***,a brief review of the application of microfluidics in comprehensive cardiovascular disease research is presented,with specific discussions of the characteristics of microfluidics for investigating cardiovascular diseases integrally,including the study of pathogenetic mechanisms,the development of accurate diagnostic methods and the establishment of therapeutic *** of critical pathogenetic mechanisms for typical cardiovascular diseases by microfluidic-based organ-on-a-chip are categorized and reviewed,followed by a detailed summary of microfluidic-based accurate diagnostic ***-assisted cardiovascular drug evaluation and screening as well as the fabrication of novel delivery vehicles are also ***,the challenges with and outlook on further advancing the use of microfluidics technology in cardiovascular disease research are highlighted and discussed.
维普期刊数据库