Endothelial dysfunction in COVID-19 calls for immediate attention:the emerging roles of the endothelium in inflammation caused by SARS-CoV-2

作     者：Weijian Hang Chen Chen Xin AZhang Dao Wen Wang Weijian Hang;Chen Chen;Xin A.Zhang;Dao Wen Wang

作者机构：Division of CardiologyDepartment of Internal Medicineand Hubei Key Laboratory of Genetics and Molecular Mechanisms of Cardiological DisordersTongji HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430030China Department of PhysiologyUniversity of Oklahoma Health Sciences CenterOklahoma CityOK 73104 

出 版 物：《Frontiers of Medicine》 (医学前沿（英文版）)

年 卷 期：2021年第15卷第4期

页      面：638-643页

核心收录：

学科分类：1002[医学-临床医学] 100201[医学-内科学(含：心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 10[医学] 

基　　金：This work was supported by grants from the National Natural Science Foundation of China(Nos.91839302,81630010,and 81790624) Tongji Hospital Clinical Research Flagship Program(No.2019CR207) 

主　　题：COVID-19 endothelial dysfunction inflammation reaction cytokine storm 

摘      要：The COVID-19 pandemic has caused numerous deaths around the world.A growing body of evidence points to the important role of overwhelming inflammatory responses in the pathogenesis of COVID-19 and the effectiveness of anti-inflammation therapy against COVID-19 is *** addition to affecting the lungs,COVID-19 can be a severe systemic inflammatory disease that is related to endothelial *** are calling for closer attention to endothelial dysfunction in COVID-19 not only for fully revealing the pathogenic mechanism of COVID-19 but also for properly adjusting the strategy of clinical intervention.