Activated Natural Killer Cells Hit Neurogenesis in the Aging Brain
激活的自然漂亮房间在变老的大脑撞击了神经发生作者机构：Center of Infectious MedicineDepartment of Medicine HuddingeKarolinska Institutet14152 StockholmSweden
出 版 物：《Neuroscience Bulletin》 (神经科学通报（英文版）)
年 卷 期：2021年第37卷第7期
页 面：1072-1074页
核心收录：
学科分类：1002[医学-临床医学] 100204[医学-神经病学] 10[医学]
基 金：Open access funding provided by Karolinska Institute
主 题：interferon Killer attributed
摘 要：Why neurogenesis is attenuated in elderly individuals is an intriguing question that has raised renewed *** associated with declined neurogenesis in the aged brain have been attributed to inflammatory cytokines[1].More recently,a specific role for interferon-y(IFN-y)produced by CD8-expressing cytotoxic T cells has been implicated[2].These observations suggest a scenario in which neurogenesis,at least in part,is regulated by immune cells within the aging *** raises several interesting questions with regards to the characteristics of specific immune cells within the brain,the signals for their expansion and maintenance,and their role in affecting neurogenesis and cognition during normal brain aging.
维普期刊数据库