多支架治疗慢性重症胰腺炎中难治性胰管狭窄的远期疗效

作     者：Costamagna G. Bulajic M. Tringali A. 孟欣颖 

作者机构：Digestive Endoscopy UnitUniversità Cattolica del Sacro CuoreA.Gemelli University HospitalLargo A.Gemelli 800168 RomeItaly Dr. 

出 版 物：《世界核心医学期刊文摘（胃肠病学分册）》 (Core Journals in Gastroenterology)

年 卷 期：2006年第2卷第9期

页      面：27-27页

学科分类：1002[医学-临床医学] 100201[医学-内科学(含：心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 10[医学] 

主　　题：多支架治疗 重症胰腺炎 胰管狭窄 远期疗效 难治性 慢性 胰管支架 肠吻合术 

摘      要：Background and Study Aims:Dominant pancreatic duct strictures located in the head of the pancreas in patients with severe chronic pancreatitis are often managed by endoscopic placement of a single plastic *** with refractory strictures after prolonged stenting require repeated stent replacement or surgical *** of multiple plastic stents has proved effective in managing postoperative biliary *** aim of this study was to investigate the feasibility,efficacy,and long-term results of multiple stenting of refractory pancreatic strictures in severe chronic *** and Methods:19 patients with severe chronic pancreatitis(16 men,three women;mean age 45 years)and with a single pancreatic stent through a refractory dominant stricture in the pancreatic head underwent the following protocol:(i)removal of the single pancreatic stent;(ii)balloon dilation of the stricture;(iii)insertion of the maximum number of stents allowed by the stricture tightness and the pancreatic duct diameter;and(iv)removal of stents after 6 to 12 ***:The median number of stents placed through the major or minor papilla was 3,with diameters ranging from 8.5 to 11.5 Fr and length from 4 to 7 *** one patient(5.5%)had persistent stricture after multiple *** a mean follow-up of 38 months after removal,84%of patients were asymptomatic,and 10.5%had symptomatic stricture *** major complications were ***:Endoscopic multiple stenting of dominant pancreatic duct strictures in chronic pancreatitis is a feasible and safe *** pancreatic stenting is promising in obtaining persistent stricture dilation on long-term follow-up in the setting of severe chronic pancreatitis.