Human umbilical cord mesenchymal stem cells as cell carriers in the treatment of gliomas: research status and prospects
作者机构：The Second Hospital of Hebei Medical UniversityShijiazhuang 050051China
出 版 物：《Journal of Translational Neuroscience》 (转化神经科学电子杂志（英文）)
年 卷 期：2020年第5卷第2期
页 面：22-33页
学科分类：1001[医学-基础医学(可授医学、理学学位)] 100101[医学-人体解剖与组织胚胎学] 10[医学]
主 题：human umbilical cord mesenchymal stem cells(HuMSCs) glioma cell carrier gene therapy targeted therapy
摘 要：Human umbilical cord mesenchymal stem cells(HuMSCs)have the multi-difFerentiation potential to differentiate into various types of cells without immune *** are considered to be an ideal source of neural stem cells and also an ideal cell carrier for gene *** of the invasive growth of brain gliomas,most of them have no obvious boundaries with normal brain *** is difficult to completely remove them by surgery and the remaining cells become the main source of tumor *** recent years,gene therapy has become a new method for the treatment of *** vector carrying the target gene is introduced into HuMSCs in a certain way to correct gene defects or play other *** differentiation potential of HuMSCs makes it an ideal source of nerve cells to play a greater role in gene therapy of ***,this article reviews the current status and prospects of HuMSCs as cell carriers in the treatment of glioma.
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