Gastrointestinal stromal tumor with multisegmental spinal metastases as first presentation:A case report and review of the literature

作     者：Yan Kong Xiao-Wei Ma Qian-Qian Zhang Yi Zhao He-Lin Feng 

作者机构：Department of Medical OncologyThe Fourth Hospital of Hebei Medical UniversityShijiazhuang 050011Hebei ProvinceChina Department of OrthopedicsThe Fourth Hospital of Hebei Medical UniversityShijiazhuang 050011Hebei ProvinceChina Department of GynecologyHebei Medical University Second Affiliated HospitalShijiazhuang 050000Hebei ProvinceChina 

出 版 物：《World Journal of Clinical Cases》 (世界临床病例杂志)

年 卷 期：2021年第9卷第6期

页      面：1490-1498页

核心收录：

学科分类：1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学] 

主　　题：Spinal metastasectomy Gastrointestinal stromal tumor Multisegmental spinal metastases Magnetic resonance imaging Case report 

摘      要：BACKGROUND Gastrointestinal stromal tumor(GIST)usually originates in the stomach,followed by the small intestine,rectum,and other parts of the gastrointestinal *** most common sites of metastasis are the liver and peritoneum,whereas spinal metastases from GIST are extremely *** SUMMARY We found a case of GIST with the first presentation of multilevel spinal metastases involving the thoracic and lumbar vertebrae.A 61-year-old Chinese man presented to our clinic because of pain in his lower back and hip for 10 d without ***,computed tomography(CT)and magnetic resonance imaging(MRI)revealed abnormal signals in the vertebral appendages of T12 and L4 accompanied by spinal canal stenosis,which was considered as tumor *** there were no metastases to vital organs,posterior thoracic and lumbar spinal decompression+adnexal mass resection+pedicle internal fixation was adopted to achieve local cure and prevent nerve *** results of histopathological studies were consistent with the metastasis of *** local recurrence or new metastases were found at the 6-mo follow-up at the surgical *** patient has no neurological symptoms at *** is worth mentioning that a rectal mass was found and surgically removed 1 mo after the patient was discharged from hospital,and the pathological diagnosis of the mass was *** By reviewing 26 previously reported cases of spinal metastasis in GIST,it was found that spinal metastasis of GIST has become more common in recent years,so the possibility of early spinal metastasis should be *** and MRI are of great value in the diagnosis of spinal metastatic tumors,and pathological biopsy is the gold standard for the diagnosis of metastatic *** is safe and feasible to treat isolated spinal metastasis in GIST by excising metastatic masses,decompressing the spinal canal,and stabilizing the spine.