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New frontiers in focal therapy for prostate cancer:Prostate-specific membrane antigen positron emission tomography/magnetic resonance imaging

作     者:Celeste Manfredi Esau Fernandez-Pascual Estefanía Linares-Espinós Felipe Couñago Juan Ignacio Martínez-Salamanca 

作者机构:Department of WomanChild and General and Specialized SurgeryUrology UnitUniversity of Campania“Luigi Vanvitelli”Naples 81110Italy Department of UrologyHospital Universitario La PazMadrid 28046Spain LYX Institute of UrologyFacultad de MedicinaUniversidad Francisco de VitoriaPozuelo de Alarcón 28223MadridSpain Radiation OncologyHospital Universitario Quirónsalud MadridPozuelo de Alarcón 28223MadridSpain Department of UrologyHospital Universitario Puerta Hierro-MajadahondaMajadahonda 28222MadridSpain 

出 版 物:《World Journal of Clinical Oncology》 (世界临床肿瘤学杂志(英文版))

年 卷 期:2021年第12卷第2期

页      面:61-68页

学科分类:0831[工学-生物医学工程(可授工学、理学、医学学位)] 100207[医学-影像医学与核医学] 1002[医学-临床医学] 08[工学] 1010[医学-医学技术(可授医学、理学学位)] 100214[医学-肿瘤学] 10[医学] 

主  题:Prostate-specific membrane antigen Positron emission tomography/magnetic resonance imaging Prostate cancer Focal therapy High-intensity focused ultrasound Cryotherapy 

摘      要:Imaging has a central role in the context of focal therapy(FT)for prostate cancer(PCa).Prostate-specific membrane antigen(PSMA)positron emission tomography/magnetic resonance imaging(PET/MRI)is a novel imaging modality that combines the morpho-functional information of MRI with the molecular characterization of *** papers reported the potential advantages of PSMA PET/MRI in different clinical *** evidence on PSMA PET/MRI is available in the setting of *** PET/MRI can be an effective imaging modality for detecting primary PCa and seems to provide accurate local staging of primary *** PET/MRI also shows high performance for restaging and detecting tumor *** higher soft-tissue contrast and the reduction of ionizing radiation are the main advantages reported in the literature compared to PET/computed *** PET/MRI could represent a turning point in the management of patients with PCa in the context of *** studies are needed to confirm its applications in this specific clinical setting.

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