Traditional Chinese medicine as supportive care for the management of liver cancer: Past, present, and future

作     者：Xia Liao Yang Bu Qingan Jia 

作者机构：Department of NutritionFirst Affiliated Hospital of Xi’an Jiaotong UniversityXi’an710061China Department of Hepatobiliary SurgeryGeneral HospitalNingxia Medical UniversityYinchuan750001China Department of Hepatobiliary SurgeryFirst Affiliated Hospital of Xi’an Jiaotong UniversityXi’an710061China 

出 版 物：《Genes & Diseases》 (基因与疾病（英文）)

年 卷 期：2020年第7卷第3期

页      面：370-379页

核心收录：

学科分类：0710[理学-生物学] 0831[工学-生物医学工程（可授工学、理学、医学学位）] 1005[医学-中医学] 1002[医学-临床医学] 1001[医学-基础医学(可授医学、理学学位)] 100214[医学-肿瘤学] 0703[理学-化学] 10[医学] 

基　　金：This research project was mainly supported by the National Natural Science Foundation of China(81502694) This research project was also partly supported by the Fundamental Research Funds for the Central Universities(1191329835) Postdoctoral Science Foundation of China(2015M570330) Key Projects of Ningxia Natural Science Foundation(NZ15130). 

主　　题：Chinese herbal medicine Hepatocellular carcinoma Molecular mechanism Network pharmacology Traditional Chinese medicine 

摘      要：Liver cancer is the sixth most commonly diagnosed cancer and the fourth leading cause of cancer death worldwide.Western medicine and therapies are the primary treatment strategies of hepatocellular carcinoma(HCC),but the general prognosis for HCC patients is still dismal.Under these circumstances,HCC prevention is particularly important.Traditional Chinese medicine(TCM)encompasses a wealth of documented therapeutic resources,and“preventative treatmentis the principle of TCM.In China,TCM has been used for HCC prevention for thousands of years,and has also been demonstrated to be effective for the treatment of HCC in modern China.However,the TCM theory for prevention and treatment of HCC is more widely accepted in China than abroad.In this review,we first summarize the herbs and ancient formulas with therapeutic effects on HCC.We also review the research status of TCM in modern medicine as well as the current obstacles in its development.Finally,we discuss the future of TCM in the context of precision and integrated medicine.After reviewing the literature,we believe that TCM,through ancient development,is an advanced method of cancer treatment with positive curative effects,despite its surrounding controversy.Furthermore,precise analyses and systematic research methods provides novel approaches to modernize TCM for the future.