Optical-resolution photo acoustic microscopy continually monitors macrophages activities of acute inflammation in vivo

作     者：Fei Duan Haosong Ma Jinde Zhang Shi Li Honghui Li Zhiyou Wu Fengqiu Hong Lvming Zeng Liming Nie 段飞;马浩淞;张锦德;李实;李宏辉;吴志友;洪凤秋;曾吕明;聂立铭

作者机构：State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics&Center for Molecular Imaging and Translational MedicineSchool of Public HealthXiamen UniversityXiamen 361102China State Key Laboratory of Precision Electronic Manufacturing Technology and EquipmentSchool of Electromechanical EngineeringGuangdong University of TechnologyGuangzhou 510006China Jiangxi Key Laboratory of Optic-Electronic and Comm unicationJiangxi Science and Technology Normal UniversityNanchang 330038China 

出 版 物：《Chinese Optics Letters》 (中国光学快报（英文版）)

年 卷 期：2020年第18卷第12期

页      面：34-38页

核心收录：

学科分类：1001[医学-基础医学(可授医学、理学学位)] 100102[医学-免疫学] 10[医学] 

基　　金：the National Natural Science Foundation of China (Nos. 91859113 and 81922034) Science Fund for Distinguished Young Scholars of Fujian Province (No. 2018J06024) Science and Technology Program of Jiangxi Province (No. 20171ACB20027) 

主　　题：photoacoustic microscopy macrophages activities vessel parameter 

摘      要：Photoacoustic imaging has been developed to image the immune study at the macro *** play diverse roles in the acute response to infection and tissue ***,macrophages activities in acute inflammation at the microscopic level still remain *** this work,we proposed optical-resolution photoacoustic microscopy to promptly monitor the labeled macrophages activities in normal and inflammatory *** result showed that many labeled macrophages emerged around the vessels firstly,then exuded into tissues,and finally disappeared in the inflammatory group injected with labeled *** summary,our method allows us to exactly image and track the immune cells of inflammatory diseases.