An electromagnetic view of relay time in propagation of neural signals

作     者：Jing-Jing Xu San-Jin Xu Fan Wang Sheng-Yong Xu 徐晶晶;徐三津;王帆;许胜勇

作者机构：School of MicroelectronicsShandong UniversityJi'nan 250100China Department of ElectronicsSchool of Electronics Engineering and Computer SciencePeking UniversityBeijing 100871China 

出 版 物：《Chinese Physics B》 (中国物理B（英文版）)

年 卷 期：2021年第30卷第2期

页      面：589-594页

核心收录：

学科分类：0809[工学-电子科学与技术（可授工学、理学学位）] 08[工学] 0805[工学-材料科学与工程（可授工学、理学学位）] 0704[理学-天文学] 

基　　金：Project supported by the National Key Research and Development Program of China(Grant Nos.2017YFA0701302 and 2016YFA0200802) the Fundamental Research Funds of Shandong University,China(Grant No.2018GN030) 

主　　题：neural signal relay propagation velocity electromagnetic field model ion channels 

摘      要：We review the experimental and computational data about the propagation of neural signals in myelinated axons in mice,cats,rabbits,and frogs published in the past five *** contrast to the natural assumption that neural signals occur one by one in time and in space,we figure out that neural signals are highly overlapped in time between neighboring *** phenomenon was occasionally illustrated in some early reports,but seemed to have been overlooked for some *** shift in time between two successive neural signals from neighboring nodes,defined as relay timeτ,was calculated to be only 16.3μs-87.0μs,i.e.,0.8%-4.4%of the average duration of an action potential peak(roughly 2 ms).We present a clearer picture of the exact physical process about how the information transmits along a myelinated axon,rather than a whole action potential peak,what is transmitted is only a rising electric field caused by transmembrane ion *** in the paper,τrepresents the waiting time until the neighboring node senses an attenuated electric field reaching the threshold to trigger the open *** mechanisms addressed in this work have the potential to be universal,and may hold clues to revealing the exact triggering processes of voltage-gated ion channels and various brain functions.