SCHISTOX: An individual based model for the epidemiology and control of schistosomiasis
作者机构：Big Data InstituteLi Ka Shing Centre for Health Information and DiscoveryUniversity of OxfordOxfordUnited Kingdom Centre for Mathematical Modelling of Infectious DiseaseLondon School of Hygiene and Tropical MedicineLondonUnited Kingdom Centre for Environment and HealthImperial College LondonLondonUnited Kingdom Department of Infectious Disease EpidemiologySchool of Public HealthFaculty of MedicineSt Mary’s CampusImperial College LondonUnited Kingdom MRC Centre for Global Infectious Disease Analysisthe Abdul Latif Jameel Institute for Disease and Emergency Analytics(J-IDEA)School of Public HealthImperial College LondonLondonW21PGUnited Kingdom
出 版 物：《Infectious Disease Modelling》 (传染病建模（英文）)
年 卷 期：2021年第6卷第1期
页 面：438-447页
学科分类：1002[医学-临床医学] 100201[医学-内科学(含：心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 10[医学]
主 题：Schistosomiasis Individual based model Mass drug administration
摘 要：A stochastic individual based model,SCHISTOX,has been developed for the study of schistosome transmission dynamics and the impact of control by mass drug *** novel aspects that can be investigated include individual level adherence and access to treatment,multiple communities,human sex population dynamics,and implementation of a potential *** of the model parameters have been estimated within previous studies and have been shown to vary between communities,such as the age-specific contact rates governing the age profiles of ***,uncertainty remains as there are wide ranges for certain parameter values and a few remain relatively *** analyse the model dynamics by parameterizing it with published parameter *** also discuss the development of SCHISTOX in the form of a publicly available open-source GitHub *** next key development stage involves validating the model by calibrating to epidemiological data.
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