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Gold Nanorods-mediated Photothermal Therapy Guided by Vascular Interventional Radiation to Inhibit Cancer Metastasis

作     者:Nomusa Mashigo Reubina Wadee 

作者机构:Department of Anatomical PathologySchool of PathologyUniversity of the Witwatersrand/National Health Laboratory ServiceJohannesburgSouth Africa Department of PathologyDivision of HaematologyFaculty of Health SciencesStellenbosch UniversityCape TownSouth Africa 

出 版 物:《Advances in Modern Oncology Research》 (现代肿瘤学研究进展(英文))

年 卷 期:2019年第5卷第3期

页      面:1-4页

学科分类:1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学] 

主  题:Selective radiotherapy Photothermal treatment Gold nanorods 

摘      要:The purpose of this study was to investigate the inhibitory effect of gold nanorods-mediated photothermal therapy on liver metastasis of colorectal cancer under the guidance of vascular interventional radiology.A total of 80 patients admitted to our hospital from February 2018 to February 2020 were selected and randomly divided into study group and control group with 40 cases each,among which the control group received 125I seed implantation combined with *** this basis,the study group were added the gold nanorods(AuNRs)to the photothermal therapy *** clinical efficacy,postoperative complications and postoperative survival rates of the two groups were *** results showed that the total clinical effective rate was 82.5%in the study group,which was significantly better than 67.5%in the control group,and the difference was statistically significant(P0.05).Therefore,under the guidance of vascular interventional radiology,Au NRs are safe and effective materials for the treatment of liver metastasis of colorectal cancer,which can reduce complications and improve postoperative survival rates.

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