Differentiation of Expression Profiles of SREBF1 and SREBF2 Gene in Chicken
作者机构：China Animal Breeding and Genetics Key Laboratory of Sichuan ProvinceSichuan Animal Science AcademyChengdu 610066China Farm Animal Genetic Resources Exploration and Innovation Key Laboratory of Sichuan ProvinceSichuan Agricultural UniversityChengdu CampusChengdu 611130China
出 版 物：《Agricultural Biotechnology》 (农业生物技术（英文版）)
年 卷 期：2020年第9卷第5期
页 面：90-93页
基 金：Key Technology Support Program of Sichuan Province(2018NZDZX0004,2016NZ0104) Financial Project of Sichuan Province(SASA2020CZYX002)
主 题：Chicken SREBF1 SREBF2 Differential expression
摘 要：Sterol regulatory element-binding factor-1 and-2(SREBF1 and SREBF2)are important transcription factors involved in the regulating lipid *** on the essential role of SREBF1 and SREBF2,we measured the mRNA expression levels of the two genes in six various tissues at different growth *** results showed that the SREBF1 and SREBF2 were expressed in all six tissues examined in Erlang mountainous chicken(SD02)at 42 d,and were expressed abundantly in the uropygial gland and liver,with relatively lowest levels of expression in the abdominal fat,sebum cutaneum and leg *** expression ratio of SREBF1 and SREBF2 in breast muscle,leg muscle,sebum cutaneum and uropygial gland exhibited adecline-rise***,in liver,the expression ratio of these two genes exhibited adecline-rise-decline***,the expression level of SREBF1 gene of all tissues was lower than that of SREBF2 except for uropygial *** findings will provide important references for further function investigation of the two genes involved in fat deposition in chickens.
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