Complete Genome Sequence of <i>Bacillus thuringiensis</i>Serovar <i>coreanensis</i>ST7 with Toxicity to Human Cancer Cells

作     者：Jing Zhang Yiping Liu Rui Liu Xu Liu Baoli Zhang Jun Zhu Jing Zhang;Yiping Liu;Rui Liu;Xu Liu;Baoli Zhang;Jun Zhu[1,3^#]

作者机构：Rice Research Institute of Sichuan Agricultural University Chengdu China Technical Center of Chengdu Customs Chengdu China State Key Laboratory of Crop Gene Exploration and Utilization in Southwest China Chengdu China 

出 版 物：《Advances in Microbiology》 (微生物学（英文）)

年 卷 期：2020年第10卷第12期

页      面：673-680页

学科分类：1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学] 

主　　题：Bacillus thuringiensis Serovar Coreanensis ST7 Gapless Chromosome Plasmid Sequences Genomic Feature Cluster of Orthologous Groups of Proteins 

摘      要：Bacillus thuringiensis (Bt) parasporal crystal proteins were well known to be toxic to certain insects and cytocidal activity against various human cancer cells. Bt serovar coreanensis ST7, non-pathogenic to insects and non-hemolytic, has an important parasporin, PS4Aa1 (Cry45Aa1), with potential toxicity to human cancer cells. In this study, we reported the feature of complete genome sequence and the cluster of orthologous groups of proteins function classification of ST7. Meanwhile, the evolutionary of ST7 was also studied. The genome data of ST7 will strongly contribute to a better understanding of the genomic diversity and evolution, and enrich the Bt genome database.