New Insight in the Assessment of Left Ventricular Function in Paradoxical Low Flow Aortic Stenosis Patients with Normal Left Ventricular Ejection Fraction: A Mini-Review

作     者：Sherif Baath Allah Enrico Mangieri Jan Fedacko Petras Lohana Mohammed Elmahal Amena Elsaady Madian Abdelrahman Jaipaul Singh Mohamed Khorshid Ram B. Singh Galaleldin Nagib Elkilany Sherif Baath Allah;Enrico Mangieri;Jan Fedacko;Petras Lohana;Mohammed Elmahal;Amena Elsaady;Madian Abdelrahman;Jaipaul Singh;Mohamed Khorshid;Ram B. Singh;Galaleldin Nagib Elkilany

作者机构：RAK Medical and Health Science University Masafi Hospital Masafi UAE Cardiac Catheterization Department Sapienza University Rome Italy Internal Medicine Department Pavol Jozef Safárik University Kosice Slovakia Internal Medicine Department Masafi Hospital Fujairah UAE London University London UK Masafi Hospital Masafi UAE Oslo University Oslo Norway School of Natural Sciences University of Central Lancashire Preston UK Faculty of Medicine Zagazig University Zagazig Egypt Halberg Hospital and Research Institute Moradabad India Gulf Medical University Ajman UAE ARE AMMC Tanta University Dubai UAE 

出 版 物：《World Journal of Cardiovascular Surgery》 (心血管外科国际期刊（英文）)

年 卷 期：2020年第10卷第12期

页      面：264-270页

学科分类：1002[医学-临床医学] 100201[医学-内科学(含：心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 10[医学] 

主　　题：Aortic Stenosis LVEF Aortic Valve Myocardial Function Global Longitudinal Stain Echocardiography 

摘      要：Paradoxical valvular aortic stenosis (VAS) is a challenging area of clinical cardiology for the practitioners. It involves a small aortic valve area, low flow rate and mean pressure gradient although there is normal left ventricular ejection fraction. The aim of this study was to assess left ventricular (LV) dysfunction in a symptomatic severe aortic valve stenosis which is of crucial importance in identifying patients at risk of heart failure, postoperative complications and increased mortality. There are new insights which are involved in assessment of LV myocardial function including global longitudinal strain (GLS) by two-dimensional speckle tracking echocardiography (2D STE), myocardial performance index (MPI) and maximum rate of LV pressure rise (+dP/dt) during isovolumetric contraction time of the LV. This information can provide both diagnostic and prognostic information in addition to standard echocardiographic and clinical parameters. However, a profound understanding of the complex interaction between loading conditions, chamber geometry and contractility is necessary for the correct interpretation of myocardial deformation in order to draw appropriate conclusions in patients with aortic valve disease. This mini review is related to new and novel insights into the assessment of left ventricular function (LVF) in paradoxical low flow aortic stenosis patients with normal left ventricular ejection fraction (LVEF).