Noncanonical antibody strategy for broad and potent neutralization of influenza virus

作     者：Jordan D.Dimitrov 

作者机构：Centre de Recherche des CordeliersINSERMSorbonne UniversitéUniversitéde ParisF-75006ParisFrance 

出 版 物：《Cellular & Molecular Immunology》 (中国免疫学杂志（英文版）)

年 卷 期：2021年第18卷第7期

页      面：1615-1617页

核心收录：

学科分类：1001[医学-基础医学(可授医学、理学学位)] 100102[医学-免疫学] 10[医学] 

基　　金：supported by the Institut National de la Sante et de la Recherche Medicale(INSERM France) 

主　　题：influenza antibodies neutral 

摘      要：Pathogens with high levels of genetic variability,such as HIV-1 and influenza virus,evade the immune system by constantly changing their proteins vulnerable to neutralization by antibodies Consequently,these highly evolvable viruses are notoriously elusive targets for *** rare cases,infection of humans with HIV-1 or influenza virus results in production of antibodies that can neutralize a very broad spectrum of viral *** antibodies are referred to as broadly neutralizing.