Interactions between commensal bacteria and viral infection:insights for viral disease control in farmed animals

作     者：Chao Ran Yu Li Xufa Ma Yadong Xie Mingxu Xie Yuting Zhang Wei Zhou Yalin Yang Zhen Zhang Li Zhou Kaijian Wei Zhigang Zhou Chao Ran;Yu Li;Xufa Ma;Yadong Xie;Mingxu Xie;Yuting Zhang;Wei Zhou;Yalin Yang;Zhen Zhang;Li Zhou;Kaijian Wei;Zhigang Zhou

作者机构：Key Laboratory for Feed Biotechnology of the Ministry of Agriculture and Rural AffairsFeed Research InstituteChinese Academy of Agricultural SciencesBeijing 100081China Sino-Norway Joint Lab on Fish Gut MicrobiotaFeed Research InstituteChinese Academy of Agricultural SciencesBeijing 100081China College of FisheriesHuazhong Agricultural UniversityWuhan 430070China State Key Laboratory of Freshwater Ecology and BiotechnologyInstitute of HydrobiologyThe Innovation Academy of Seed DesignChinese Academy of SciencesWuhan 430072China 

出 版 物：《Science China(Life Sciences)》 (中国科学（生命科学英文版）)

年 卷 期：2021年第64卷第9期

页      面：1437-1448页

核心收录：

学科分类：090603[农学-临床兽医学] 09[农学] 0906[农学-兽医学] 

基　　金：supported by the National Key R&D Program of China(2018YFD0900400) the National Natural Science Foundation of China(31925038,31872584,31972807) 

主　　题：virus intestinal microbiota commensal bacteria farmed animals probiotics 

摘      要：Viral diseases cause serious economic loss in farmed animals ***,the efficacy of remedies for viral infection in farmed animals is limited,and treatment strategies are generally lacking for aquatic *** of commensal microbiota and viral infection have been studied in recent years,demonstrating a third player in the interaction between hosts and ***,we discuss recent developments in the research of interactions between commensal bacteria and viral infection,including both promotion and inhibition effect of commensal bacteria on viral pathogenesis,as well as the impact of viral infection on commensal *** antiviral effect of commensal bacteria is mostly achieved through priming or regulation of the host immune responses,involving differential microbial components and host signaling pathways,and gives rise to various antiviral ***,we summarize studies related to the interaction between commensal bacteria and viral infection in farmed animals,including pigs,chickens,fish and invertebrate *** studies in this area will deepen our understanding of antiviral immunity of farmed animals in the context of commensal microbiota,and promote the development of novel strategies for treatment of viral diseases in farmed animals.