International current of the genotoxicity testing

作     者：HayaM 

作者机构：DivisionofGeneticsandMutagenesisBiologicalSafetyResearchCenterNationalInstituteofHealthSciencesTok 

出 版 物：《中国药理学与毒理学杂志》 (Chinese Journal of Pharmacology and Toxicology)

年 卷 期：2002年第16卷第6期

页      面：412-412页

核心收录：

学科分类：100405[医学-卫生毒理学] 1004[医学-公共卫生与预防医学(可授医学、理学学位)] 10[医学] 

主　　题：致诱变性试验 国际合作 遗传毒性 

摘      要：One of the goals of the genetic toxicology is to assess the risk to humans that derives from genotoxic *** risk involves both somatic and germ cells,with damage to the former resulting in cancer and damage to the latter in adverse effects that could be transmitted through *** is necessary to consider not only direct effects,but also effects that are the result of analtered *** perform an accurate risk *** is necessary to evaluate genotoxic hazards in ways that are appropriate both methodologically and *** establishing a genotoxicity assay system,international cooperation is important because it enables us to incorporate the thoughts of specialists everywhere and to learn of specific regional *** I will introduce the “Guidance on a Strategy for Testing of Chemicals for Mutagenicity recently reported by the UK Committee on Mutagenicity (COM) and also I will briefly summarize the activities of the International Workshop on Genotoxicity Test Procedures(IWGTP).The first and the second workshops focused on *** started to include the strategic issues as well as procedures in the third *** with the 3rd IWGT,the workshop will become an activity of the International Association of EMSs.