Neurochip Based on Light-addressable Potentiometric Sensor

作     者：Qingjun Liu~(1,2) Hua Cai~1 Ying Xu~(1,2) Lifeng Qin~1 Lijiang Wang~1 Ping Wang~(1,2) (1.Biosensor National Special Laboratory,Key Laboratory of Biomedical Engineering of Education Ministry,Department of Biomedical Engineering,Zhejiang University,Hangzhou 310027,China) (2 State Key Laboratory of Transducer Technology,Chinese Academy of Sciences,Shanghai 200050,China) 

出 版 物：《稀有金属材料与工程》 (Rare Metal Materials and Engineering)

年 卷 期：2006年第S3期

页      面：413-416页

核心收录：

学科分类：080202[工学-机械电子工程] 08[工学] 0802[工学-机械工程] 

主　　题：neurochip cell-based biosensor hippocampal neurons light-addressable potentiometric sensor 

摘      要：A novel neurochip based on light addressable potentiometric sensor （LAPS） is *** its light addressable *** problems of the limitations of restricted discrete active sites of current neurochips,such as microelectrode array and field effect transistor array can be settled *** on the theoretical analysis of the interface between cells and LAPS,spontaneously discharges of hippocampal neurons induced by Mg~ 2+)-free media treatment were recorded by *** results demonstrate that this kind of neurochip has potential to monitor electrophysiology of cultured cells in a non-invasive way.