An optimal control model with cost effectiveness analysis of Maize streak virus disease in maize plant
作者机构：Department of MathematicsCollege of Natural and Computational SciencesUniversity of GondarGondarEthiopia Pan African University Institute of Basic SciencesTechnology and InnovationNairobiKenya Department of Plant SciencesCollege of Agriculture and Rural TransformationUniversity of GondarGondarEthiopia Department of StatisticsCollege of Natural and Computational SciencesUniversity of GondarGondarEthiopia
出 版 物：《Infectious Disease Modelling》 (传染病建模（英文）)
年 卷 期：2021年第6卷第1期
页 面：169-182页
主 题：MSV Eco-epidemiological model Optimal control theory Numerical simulation Cost-effectiveness analysis
摘 要：In this paper we formulated and analyzed an optimal deterministic eco-epidemiological model for the dynamics of maize streak virus(MSV)and examine the best strategy to fight maize population from maize streak disease(MSD).The optimal control model is developed with three control interventions,namely prevention(u_(1)),quarantine(u_(2))and chemical control(u_(3)).To achieve an optimal control strategy,we used the Pontryagin’s maximum principle obtain the Hamiltonian,the adjoint variables,the characterization of the controls and the optimality *** simulations are performed using Forward-backward sweep iterative *** findings show that each integrated strategy is able to mitigate the disease in the specified *** due to limited resources,it is important to find a cost-effective *** Incremental Cost-Effectiveness Ratio(ICER)a cost-effectiveness analysis is investigated and determined that the combination of prevention and quarantine is the best cost-effective strategy from the other integrated ***,policymakers and stakeholders should apply the integrated intervention to stop the spread of MSV in the maize population.
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